Time that physicians start following the science. Study using data from the Multi-ethnic Study of Atherosclerosis was used to assess hormones and fatty liver in men and women. Increasing bioavailable Testosterone levels in women was found to be associated with increasing fatty liver in post-menopausal women. The opposite was found to be true in men. Higher Estradiol levels were found to be associated with increased fatty liver in both sexes. However, the statistical significance was higher with men. Higher SHBG was associated with lower fatty liver incidence in men.
Fructose upregulates fructokinase activity and this increase liver triglyceride production increasing non-alcoholic fatty liver disease also known as NAFLD.
with an estimated 25% of Americans with non-alcoholic fatty liver disease (NAFLD), elevated liver enzymes are becoming a more common finding. Nice review article on what the tests mean and what disease are underlying.
non-alcoholic fatty liver disease the result of Metabolic syndrome. New epidemic associated with obesity.
Scary statistics about the children of America.
Low Testosterone increased nonalcoholic fatty liver disease in men. The prevalence of NAFLD reached 85% with Total Testosterone was < 300 ng/dl. Free Testosterone required a greater drop to increase the NAFLD, but it to still was found to be associated.
in those with nonalcoholic fatty liver disease, low adiponectin is associated with the insulin resistance, not the NAFLD. But of course, insulin resistance leads to NAFLD
The fastest growing liver disease today is NAFLD, which is a direct result of the rising obesity epidemic. This is a good review of the current understanding on the pathophysiology of NAFLD.
good read, though only abstract available here. Elevated Ferritin is usually caused by inflammation, chronic alcohol use, liver disease, renal failure, MetS, or cancer.